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EMPACT-Syndrom
ββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββ
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Das EMPACT-Syndrom, ein Akronym fΓΌr Erythema exsudativum Multiforme durch Phenytoin And (und) Craniale StrahlenTherapie, ist eine akute entzΓΌndliche Reaktion der Haut auf eine Bestrahlung des Kopfes bei gleichzeitiger Gabe des Arzneimittels Phenytoin, das gegen KrampfanfΓ€lle eingesetzt wird.
Die Bezeichnung wurde erstmals im Jahre 2004 von I. Ahmed und Mitarbeitern vorgeschlagencite-ref-1[1] fΓΌr das Auftreten eines Erythema multiforme bei einer Bestrahlungstherapie des GehirnschΓ€dels unter Einnahme von Phenytoin.cite-ref-2[2]
Differential-diagnostisch abzugrenzen ist das DRESS-Syndrom.
Contents
β’ Literatur
β’ Einzelnachweise
ββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββ
Literatur
β’ A. Vilas-Sueiro, I. VΓ‘zquez-Osorio, J. M. SuΓ‘rez-PeΓ±aranda, D. SΓ‘nchez-Aguilar: Erythema Multiforme Associated With Phenytoin and Cranial Radiation Therapy (EMPACT syndrome) in a Patient With Lung Cancer. In: Actas dermo-sifiliograficas. Bd. 107, Nr. 2, MΓ€rz 2016, S. 169β170, doi:10.1016/j.ad.2015.06.010, PMID 26593687.
β’ A. J. Bishop, M. Chang, M. E. Lacouture, C. A. Barker: EMPACT syndrome: limited evidence despite a high-risk cohort. In: Journal of neuro-oncology. Bd. 119, Nr. 1, August 2014, S. 129β134, doi:10.1007/s11060-014-1457-7, PMID 24792490, PMC 4712043 (freier Volltext).
Einzelnachweise
cite-note-11. β I. Ahmed, J. Reichenberg, A. Lucas, J. M. Shehan: Erythema multiforme associated with phenytoin and cranial radiation therapy: a report of three patients and review of the literature. In: International journal of dermatology. Bd. 43, Nr. 1, Januar 2004, S. 67β73, PMID 14693027 (Review).
cite-note-22. β K. AydoΔan, S. Vatansever, S. B. Adim, H. Saricaoglu: Empact syndrome: a case report and review of the literature. In: International journal of dermatology. Bd. 49, Nr. 8, August 2010, S. 945β949, doi:10.1111/j.1365-4632.2009.04338.x, PMID 21128922 (Review).
cite-note-33. β G. Fabbrocini, L. Panariello, M. Pensabene, R. Lauria, E. Matano, D. Martellotta, D. Bianca, S. De Placido, F. Ayala: EMPACT syndrome associated with phenobarbital. In: Dermatitis : contact, atopic, occupational, drug. Bd. 24, Nr. 1, 2013 Jan-Feb, S. 37β39, doi:10.1097/DER.0b013e31827ede32, PMID 23340399.